Ryu Kazuteru, Takeshita Hideyuki, Takubo Yoshinori, Hirata Masazumi, Taniguchi Daigo, Masuzawa Naoko, Kishimoto Mitsuo, Kubo Toshikazu
Department of Orthopedic Surgery, Otsu Municipal Hospital, 9-9 Motomiya, Otsu, 520-0804, Japan.
Mod Rheumatol. 2005;15(4):290-3. doi: 10.1007/s10165-005-0401-2.
The development of multiple large tophi in patients with gout is rare. We report magnetic resonance (MR) and histological features of large subcutaneous tophi in a 32-year-old male patient with no known arthritis. His subcutaneous lesions were confused with a neoplastic process, evaluated by MR imaging, and surgically excised after biopsy. The honeycomb-like appearance on the gadolinium-enhanced images may reflect the characteristic multilobular structure of the tophi composed of avascular urate deposits and surrounding vascularized granulation tissue.
痛风患者出现多个大痛风石的情况较为罕见。我们报告了一名32岁无已知关节炎的男性患者皮下大痛风石的磁共振（MR）及组织学特征。他的皮下病变通过MR成像评估，与肿瘤性病变相混淆，并在活检后进行了手术切除。钆增强图像上的蜂窝状外观可能反映了痛风石由无血管尿酸盐沉积物和周围血管化肉芽组织组成的特征性多叶结构。
