Hashimoto Yoshiko, Hashimoto Naoko, Furuta Shunsuke, Sugawara Takeaki, Kosugi Nobuharu, Hata Maki, Eguchi Masanobu
Department of Rheumatology, Numazu City Hospital, 550 Harunoki, Aza, Higashi-shiiji, Numazu, 410-0302, Japan.
Mod Rheumatol. 2005;15(6):435-9. doi: 10.1007/s10165-005-0432-8.
A 56-year-old Japanese man was admitted to our hospital due to a fever of unknown origin. He had had a history of extranodal natural killer (NK)/T-cell lymphoma, nasal type, and had been in complete remission for 7 years until June 2003, when he developed high fever, eyelid swelling, and muscular weakness. Serum creatine kinase levels were elevated. Histopathological examination of skin and muscle biopsy specimens revealed subcutaneous infiltration of lymphoid cells positive for CD3, CD56, and Epstein-Barr virus-encoded small nuclear RNA-1. We report this unique case of Epstein-Barr virus-associated lymphoma mimicking dermatomyositis.
一名56岁的日本男性因不明原因发热入住我院。他有鼻型结外自然杀伤（NK）/T细胞淋巴瘤病史，至2003年6月一直处于完全缓解状态达7年，之后出现高热、眼睑肿胀和肌肉无力。血清肌酸激酶水平升高。皮肤和肌肉活检标本的组织病理学检查显示，CD3、CD56和爱泼斯坦-巴尔病毒编码的小核RNA-1阳性的淋巴细胞皮下浸润。我们报告了这例模仿皮肌炎的爱泼斯坦-巴尔病毒相关淋巴瘤的独特病例。
