Nick A M, Bruner J P, Moses R, Yang E Y, Scott T A
Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Ultrasound Obstet Gynecol. 2006 Nov;28(6):821-5. doi: 10.1002/uog.2858.
To determine in fetuses with gastroschisis the association between intra-abdominal bowel dilation in the second trimester and neonatal bowel atresia.
We reviewed ultrasound and medical records of fetuses with gastroschisis from January 1998 to August 2004. Fetuses with intra-abdominal bowel dilation in the second trimester were identified and followed into the neonatal period.
We identified 58 mother-infant pairs showing fetal gastroschisis, with at least one prenatal ultrasound at our hospital and which were delivered there, or were transported there as newborns. Forty-eight of the 58 fetuses had no intra-abdominal bowel dilation and none of these neonates had bowel atresia. Ten of the 58 fetuses had intra-abdominal bowel dilation and all had bowel atresia at birth (P<0.0001). In eight cases in which ultrasound was performed at <25 weeks' gestation, intra-abdominal bowel dilation was already present.
Intra-abdominal bowel dilation in the second trimester predicts neonatal bowel atresia in fetuses with gastroschisis.
确定腹裂胎儿孕中期腹腔内肠管扩张与新生儿肠闭锁之间的关联。
回顾1998年1月至2004年8月腹裂胎儿的超声及病历资料。识别出孕中期腹腔内肠管扩张的胎儿，并随访至新生儿期。
我们确定了58对母婴，显示胎儿腹裂，在我院至少有一次产前超声检查且在我院分娩，或新生儿期转运至我院。58例胎儿中48例无腹腔内肠管扩张，这些新生儿均无肠闭锁。58例胎儿中有10例有腹腔内肠管扩张，且所有出生时均有肠闭锁（P<0.0001）。在8例妊娠<25周时进行超声检查的病例中，腹腔内肠管扩张已存在。
孕中期腹腔内肠管扩张可预测腹裂胎儿的新生儿肠闭锁。
