Baldassano Claudia F
Department of Psychiatry, Outpatient Program, University of Pennsylvania, PA, USA.
J Clin Psychiatry. 2006;67 Suppl 11:8-11.
Among patients with bipolar disorder, comorbid conditions are common. Comorbidity is associated with a more difficult course of illness (such as longer episodes, shorter time euthymic, and earlier age at onset) and an increase in related problems (such as suicidality and violence). Data from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) reveal that anxiety disorders, attention-deficit/hyperactivity disorder, and substance and alcohol use disorder are conditions that commonly co-occur with bipolar disorder. This article details these findings and discusses the complications associated with these comorbid conditions. STEP-BD data about gender differences are also discussed, and correlates of suicidal ideation among patients entering the program are described.
在双相情感障碍患者中，共病情况很常见。共病与更艰难的病程（如发作时间更长、心境正常时间更短以及发病年龄更早）以及相关问题（如自杀倾向和暴力行为）的增加有关。双相情感障碍系统治疗强化项目（STEP - BD）的数据显示，焦虑症、注意力缺陷多动障碍以及物质和酒精使用障碍是常与双相情感障碍共病的情况。本文详细阐述了这些发现，并讨论了与这些共病情况相关的并发症。还讨论了STEP - BD关于性别差异的数据，并描述了进入该项目的患者中自杀意念的相关因素。
