Dhalla Shayesta, Chan Keith J, Montaner Julio S G, Hogg Robert S
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada.
Complement Ther Clin Pract. 2006 Nov;12(4):242-8. doi: 10.1016/j.ctcp.2006.05.002. Epub 2006 Jul 10.
In 2002, the British Columbia (BC) Centre for Excellence in HIV/AIDS collected final detailed data on complementary and alternative medicine (CAM) use in their HIV treatment program. This cross-sectional study of 682 participants examines types and determinants of CAM use in this program, and examines adverse effects associated with CAM use and antiretroviral therapy (ART). Among the 47% ever CAM users in the included population, vitamins/minerals (81%), meditation/yoga (36%), massage (31%), marijuana (30%), dietary supplements (24%), and herbal medicines (19%), were most commonly used. Multivariate analysis indicated CAM users were less likely to have low education (AOR=0.51), more likely to be unemployed (AOR=1.52), more likely to have been on ART longer (AOR=1.19), and more likely to experience objective, action-requiring (OA) side effects (AOR=1.45). CAM use is common. Both patients and health professionals should be aware of potential toxicities and drug interactions related to the use of CAM and HIV/AIDS treatment.
2002年，不列颠哥伦比亚省（BC）艾滋病卓越中心收集了其艾滋病治疗项目中补充和替代医学（CAM）使用情况的最终详细数据。这项对682名参与者的横断面研究考察了该项目中CAM使用的类型和决定因素，并研究了与CAM使用及抗逆转录病毒疗法（ART）相关的不良反应。在所纳入人群中，曾使用CAM的人占47%，其中最常用的有维生素/矿物质（81%）、冥想/瑜伽（36%）、按摩（31%）、大麻（30%）、膳食补充剂（24%）和草药（19%）。多变量分析表明，使用CAM的人受教育程度低的可能性较小（比值比[AOR]=0.51），失业的可能性较大（AOR=1.52），接受ART治疗时间较长的可能性较大（AOR=1.19），出现需要采取行动的客观（OA）副作用的可能性较大（AOR=1.45）。CAM的使用很普遍。患者和医护人员都应意识到与使用CAM及艾滋病治疗相关的潜在毒性和药物相互作用。
