Pontone Gregory, Williams James R, Bassett Susan Spear, Marsh Laur
Department of Psychiatry and Behavioral Sciences, Bloomberg School of Public Health, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Neurology. 2006 Oct 10;67(7):1258-61. doi: 10.1212/01.wnl.0000238401.76928.45.
In patients with Parkinson disease (PD), impulse control disorders (ICDs) such as hypersexuality and pathologic gambling and shopping can be devastating complications of antiparkinsonian treatment. To improve their detection, we investigated clinical features associated with ICDs. Subjects were participants in a longitudinal study of PD. ICDs were associated with use of dopamine agonists and depressed mood, disinhibition, irritability, and appetite disturbance.
在帕金森病(PD)患者中,冲动控制障碍(ICD),如性欲亢进、病理性赌博和购物,可能是抗帕金森病治疗的严重并发症。为了提高对它们的检测,我们研究了与ICD相关的临床特征。研究对象是参与PD纵向研究的患者。ICD与多巴胺激动剂的使用以及情绪低落、去抑制、易怒和食欲紊乱有关。