Resch T A, Delle M, Falkenberg M, Ivancev K, Konrad P, Larzon T, Lönn L, Malina M, Nyman R, Sonesson B, Thelin S
Department of Vascular Diseases, Malmö University Hospital, Malmö, Sweden.
J Cardiovasc Surg (Torino). 2006 Oct;47(5):503-8.
Endovascular repair of complicated type B dissections has evolved as a promising alternative to open repair. Previous studies have indicated that continued false lumen flow is a predictor of continued aortic dilatation and risk of rupture during follow-up. This multicenter study was conducted to analyze the postoperative changes of the false lumen after endografting of complicated type B dissections.
All patients treated with endovascular stent grafts for thoracic type B dissections at 5 major Vascular Centers in Sweden were identified through local databases. Review of charts and all available pre- and postoperative CT scans were performed to identify demographics, indications for repair as well as postoperative changes of the aorta and false lumen.
A total of 129 patients treated for type B dissections between 1994 and December 2005 were identified. Median radiological follow-up was 14 months. Fourteen patients died perioperatively leaving 115 patients available for analysis. Seventy-four of these had CT imaging of sufficient quality for morphological analysis. The vast majority of acute patients were treated for rupture or end-organ ischemia whereas most chronic patients were treated for asymptomatic aneurysms. In 80% of patients, the false lumen thrombosed along the stent graft but it remained perfused distal to the stent graft fixation in 50% of patients. Only 5% of patients presented with aortic enlargement of the stent grafted area when adequate proximal sealing was achieved. The distal, uncovered aorta displayed expansion in 16% of patients.
The stent grafted thoracic aorta after type B dissection appears to be stabilized by covering the primary entry site with a stent graft in the majority of both acute and chronic dissections. The uncovered portion of the aorta distal to the stent graft, however, remains at risk of continuous dilatation. Stent grafting for complicated type B thoracic dissections seems to be a treatment option with reasonable morbidity and mortality even though the incidence of severe complications is still significant.
复杂B型夹层的血管腔内修复已发展成为一种有前景的开放修复替代方法。既往研究表明,假腔持续血流是随访期间主动脉持续扩张和破裂风险的预测指标。本多中心研究旨在分析复杂B型夹层血管腔内修复术后假腔的变化。
通过瑞典5个主要血管中心的本地数据库,识别所有接受血管腔内支架植入治疗胸段B型夹层的患者。回顾病历及所有可用的术前和术后CT扫描,以确定人口统计学资料、修复指征以及主动脉和假腔的术后变化。
共识别出1994年至2005年12月期间接受B型夹层治疗的129例患者。影像学随访的中位时间为14个月。14例患者围手术期死亡,剩余115例患者可供分析。其中74例患者的CT成像质量足以进行形态学分析。绝大多数急性患者因破裂或终末器官缺血接受治疗,而大多数慢性患者因无症状动脉瘤接受治疗。80%的患者假腔沿支架移植物形成血栓,但50%的患者在支架移植物固定远端仍有血流灌注。当近端密封良好时,仅5%的患者出现支架植入区域的主动脉扩张。16%的患者远端未覆盖的主动脉出现扩张。
在大多数急性和慢性夹层中,B型夹层术后植入支架的胸主动脉似乎通过用支架移植物覆盖主要入口部位而得以稳定。然而,支架移植物远端未覆盖的主动脉部分仍有持续扩张的风险。尽管严重并发症的发生率仍然较高,但复杂B型胸段夹层的支架植入似乎是一种具有合理发病率和死亡率的治疗选择。