Siakkou H, Ulrich R, Uelze A, Möhring R, Rosenthal S
Department of Cell Differentiation, Academy of Sciences, Berlin, German Democratic Republic.
Acta Virol. 1990 May;34(3):256-62.
Hybrid proteins composed of beta-galactosidase and polypeptides of the bovine leukaemia virus (BLV) including those of the main core protein p24, the envelope protein gp51 and the transmembrane protein gp30 were produced in Escherichia coli and immunologically characterized. The hybrid proteins were immunologically reactive with sera from cattle naturally infected with BLV, demonstrating a possible use for diagnosis of BLV infection. Detection of antibodies was most sensitive with the p24 derivative.
由β-半乳糖苷酶与牛白血病病毒（BLV）的多肽组成的杂合蛋白，包括主要核心蛋白p24、包膜蛋白gp51和跨膜蛋白gp30，在大肠杆菌中产生并进行了免疫特性分析。这些杂合蛋白与自然感染BLV的牛血清具有免疫反应性，表明其在诊断BLV感染方面可能具有应用价值。用p24衍生物检测抗体最为敏感。
