经阴道超声能量多普勒评估体外受精治疗女性年龄与卵泡周围血流的关系
Power doppler ultrasound assessment of the relationship between age and ovarian perifollicular blood flow in women undergoing in vitro fertilization treatment.
作者信息
Costello Michael F, Shrestha Sanu M, Sjoblom Peter, McNally Glen, Bennett Michael J, Steigrad Stephen J, Hughes Graeme J
机构信息
School of Women's and Children's Health, Division of Obstetrics and Gynaecology, Level 1 Women's Health Institute, Royal Hospital for Women, Randwick, Sydney, NSW, Australia, 2031.
出版信息
J Assist Reprod Genet. 2006 Sep-Oct;23(9-10):359-65. doi: 10.1007/s10815-006-9067-8. Epub 2006 Oct 11.
Abstract
PURPOSE
To examine the relationship between age and ovarian perifollicular blood flow (PFBF) in women undergoing IVF.
METHODS
Serial transvaginal power Doppler ultrasound (PDU) scans to assess ovarian PFBF were performed prospectively throughout the follicular phase of ovarian stimulation in women undergoing IVF. The ultrasound assessment days were categorized according to day of hCG trigger.
RESULTS
A total of 1050 ovarian follicles from 34 women undergoing one IVF treatment cycle were used for data analysis. The median age of the women was 38.5 years, ranging from 28 years to 44 years. There was a significant negative correlation between age and ovarian PFBF on the day of hCG trigger or trigger day minus 1, but not beforehand during the follicular phase.
CONCLUSIONS
There was a significant negative correlation between age and ovarian PFBF in women undergoing IVF which was only observed very late in the follicular phase of ovarian stimulation.
摘要
目的
研究接受体外受精（IVF）的女性年龄与卵巢卵泡周围血流（PFBF）之间的关系。
方法
对接受IVF的女性在卵巢刺激卵泡期前瞻性地进行连续经阴道能量多普勒超声（PDU）扫描，以评估卵巢PFBF。超声评估日根据人绒毛膜促性腺激素（hCG）触发日进行分类。
结果
对34名接受一个IVF治疗周期的女性的总共1050个卵巢卵泡进行数据分析。这些女性的中位年龄为38.5岁，年龄范围为28岁至44岁。在hCG触发日或触发日前一天，年龄与卵巢PFBF之间存在显著负相关，但在卵泡期之前不存在。
结论
接受IVF的女性年龄与卵巢PFBF之间存在显著负相关，且仅在卵巢刺激卵泡期的很晚阶段才观察到这种相关性。
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