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精心挑选的睾丸内病变可通过连续超声检查安全处理。

Carefully selected intratesticular lesions can be safely managed with serial ultrasonography.

作者信息

Connolly Stephen S, D'Arcy Frank T, Gough Niall, McCarthy Peter, Bredin Hugh C, Corcoran Michael O

机构信息

Department of Urology, University College Hospital Galway, National University of Ireland, Galway, Ireland.

出版信息

BJU Int. 2006 Nov;98(5):1005-7; discussion 1007. doi: 10.1111/j.1464-410X.2006.06451.x.

Abstract

OBJECTIVE

To evaluate a policy of conservative non-operative management for incidental, impalpable, < 1 cm, intratesticular pathology.

PATIENTS AND METHODS

We retrospectively reviewed all scrotal ultrasonograms within an 8-year period to identify all radiological lesions of < 1 cm within the testis. All palpable lesions and those accompanied by elevated tumour markers or disseminated malignancy were managed surgically. The remaining incidentally detected lesions were followed with a protocol of serial ultrasonography (US).

RESULTS

Of 1544 scans reviewed, 12 (0.8%) lesions suitable for observational management were identified. The mean (range) age of the patients was 54 (34-76) years. The indication for US was suspected epididymitis in five, contralateral epididymal cyst in five and infertility in two patients. The mean (range) size of the lesion was 4.9 (1.5-9.8) mm. Three anechoic lesions were consistent with intratesticular cysts, and each was followed with no change to a mean (range) follow-up of 26 (12-48) months. Eight hypoechoic lesions were followed to a mean of 34 (4-72) months, and only one showed growth on repeat US after an interval of 4 months, and was diagnosed as a 1.0-cm seminoma after orchidectomy. One hyperechoic lesion remains unchanged at 6 months of follow-up.

CONCLUSION

Supported by previous reports suggesting that most testis lesions of < 1 cm are benign, we managed a series of carefully selected intratesticular lesions conservatively, the behaviour in most being in keeping with benign pathology.

摘要

目的

评估对偶然发现的、不可触及的、直径<1 cm的睾丸内病变采取保守非手术治疗的策略。

患者与方法

我们回顾性分析了8年间所有阴囊超声检查结果,以确定睾丸内所有直径<1 cm的放射学病变。所有可触及的病变以及伴有肿瘤标志物升高或弥漫性恶性肿瘤的病变均接受手术治疗。其余偶然发现的病变采用系列超声检查(US)方案进行随访。

结果

在1544次检查中,发现12例(0.8%)适合观察性管理的病变。患者的平均(范围)年龄为54岁(34 - 76岁)。超声检查的指征分别为5例疑似附睾炎、5例对侧附睾囊肿和2例不育症。病变的平均(范围)大小为4.9 mm(1.5 - 9.8 mm)。3例无回声病变符合睾丸内囊肿,每例随访期间均无变化,平均(范围)随访26个月(12 - 48个月)。8例低回声病变平均随访34个月(4 - 72个月),仅1例在4个月后复查超声时显示生长,睾丸切除术后诊断为1.0 cm精原细胞瘤。1例高回声病变在随访6个月时无变化。

结论

先前的报告表明大多数直径<1 cm的睾丸病变是良性的,在此支持下,我们对一系列精心挑选的睾丸内病变进行了保守治疗,大多数病变的表现符合良性病理特征。

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