Francis Jasmine H, Latkany Paul A, Rosenthal Jeanne L
New York Eye and Ear infirmary, New York University Medical Center, New York, NY 10016 USA.
Br J Ophthalmol. 2007 Jun;91(6):818-21. doi: 10.1136/bjo.2006.103994. Epub 2006 Oct 11.
The complications of intraocular silicone oil include emulsification, which may lead to vision-threatening disorders such as keratopathy, secondary glaucoma and retinopathy. The authors study the effect of mechanical energy from surgical instruments on the emulsification of silicone oil.
Three different handpieces (phacofragmentation, phacoemulsification, high-speed vitrectomy) were placed at the interface of balanced salt solution and silicone oil (1000 and 5000 cst, 200 fluid; Dow Corning). The phacofragmentation handpiece was evaluated over different ultrasound powers and duration. Emulsification was quantified with phase-contrast microscopy and manual counting of digital photographs by a masked examiner. In addition, phacoemulsification was performed in the anterior chamber of a human ex vivo eye with full-fill silicone oil.
Emulsification increases with higher phacofragmentation power and duration and is greater for 1000 cst silicone oil. Emulsification of silicone oil occurs with phacoemulsification and high-speed vitrectomy handpieces.
The energy from surgical handpieces is sufficient to result in silicone oil emulsification.
眼内硅油的并发症包括乳化，这可能导致威胁视力的疾病，如角膜病变、继发性青光眼和视网膜病变。作者研究手术器械产生的机械能对硅油乳化的影响。
将三种不同的机头（晶状体破碎、超声乳化、高速玻璃体切割）置于平衡盐溶液与硅油（1000和5000厘沲，200毫升；道康宁公司）的界面处。对晶状体破碎机头在不同超声功率和持续时间下进行评估。乳化程度通过相衬显微镜定量，并由一名不知情的检查人员对数码照片进行手动计数。此外，在充满硅油的人离体眼的前房进行超声乳化。
乳化程度随晶状体破碎功率和持续时间的增加而增加，对于1000厘沲的硅油更为明显。硅油乳化也发生在超声乳化和高速玻璃体切割机头上。
手术机头产生的能量足以导致硅油乳化。
