Ferrara Mariantonia, Coco Giulia, Sorrentino Tania, Jasani Kirti M, Moussa George, Morescalchi Francesco, Dhawahir-Scala Felipe, Semeraro Francesco, Steel David H W, Romano Vito, Romano Mario R
Manchester Royal Eye Hospital, Oxford Road, Manchester M13 9WL, UK.
Department of Clinical Science and Translational Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
J Clin Med. 2022 Sep 5;11(17):5234. doi: 10.3390/jcm11175234.
Silicone oils (SO) are used as long-term intraocular tamponades and have an irreplaceable role in vitreoretinal surgery. They can, however, be associated with multiple and potentially severe complications, involving different ocular tissues, in particular retina and cornea. Recent advances in ophthalmic imaging have allowed the precise characterization of retinal and corneal microstructural changes, at a subclinical level. This detailed analysis of SO-related retinal and corneal changes has improved our understanding of their pathogenesis and offer the potential for optimized monitoring and management of patients with SO-filled eyes. This review aims to provide clinicians and ophthalmic scientists with an updated and comprehensive overview of the corneal and retinal changes associated with SO tamponade.
硅油（SO）被用作长期眼内填充物，在玻璃体视网膜手术中发挥着不可替代的作用。然而，它们可能会引发多种潜在的严重并发症，累及不同的眼部组织，尤其是视网膜和角膜。眼科成像技术的最新进展使得在亚临床水平上能够精确表征视网膜和角膜的微观结构变化。对与硅油相关的视网膜和角膜变化进行的详细分析，增进了我们对其发病机制的理解，并为优化对硅油填充眼患者的监测和管理提供了可能。本综述旨在为临床医生和眼科科学家提供与硅油填充相关的角膜和视网膜变化的最新全面概述。
