Klein D, MacDonald A, Drummond N, Cave A
Continuous Professional Learning, Faculty of Medicine and Dentistry, 2J3 Walter Mackenzie Centre Edmonton, Alberta T6G 2R7 Canada.
Fam Pract. 2006 Dec;23(6):659-65. doi: 10.1093/fampra/cml048. Epub 2006 Oct 11.
Cyclo-oxygenase-2 inhibiting (COXIB) anti-inflammatories have been the drug class prescribed for a large number of cases of musculoskeletal (MSK) disorders in Canada over the past 5 years. The Alberta Improvements for MSK Disorders (AIMS) initiative sought to better understand the COXIB prescribing situation by funding several studies. The objective of this qualitative study was to determine the factors underlying primary care physicians' medication prescribing behaviour during an office visit for an MSK disorder, with particular emphasis on the prescribing of COXIBs.
The target respondents were Alberta primary care physicians chosen from a stratified random sample to meet a wide range of characteristics. Individual, semi-structured interviews were used to assess decision pathways in four real cases chosen by the physician. A total of 19 interviews were conducted and analysed using an analytic inductive approach.
Factors judged as being important to decision pathways in relation to COXIB prescribing for MSK disease included safety, patient characteristics, affordability to patients, availability of samples, drug company marketing practices, habit formation, time contstraints, previous clinical experience of doctors and/or patient with certain drugs and doctors' perception of absolute versus relative risk. Interpretation. Most physicians preferentially prescribed COXIBs subsequent to a complicated, multifactorial, but essentially patient-centred, decision-making process.
在过去5年中,环氧化酶-2抑制(COXIB)类抗炎药一直是加拿大大量肌肉骨骼(MSK)疾病病例所开具的药物类别。艾伯塔省肌肉骨骼疾病改善(AIMS)倡议通过资助多项研究,试图更好地了解COXIB的处方情况。这项定性研究的目的是确定在因MSK疾病进行门诊就诊期间,基层医疗医生用药处方行为的潜在因素,特别强调COXIB的处方情况。
目标受访者是从分层随机样本中选取的艾伯塔省基层医疗医生,以满足广泛的特征。采用个人半结构化访谈来评估医生选择的四个实际病例中的决策途径。共进行了19次访谈,并使用分析归纳法进行分析。
在MSK疾病的COXIB处方决策途径中,被认为重要的因素包括安全性、患者特征、患者的可承受性、样品的可获得性、制药公司的营销做法、习惯形成、时间限制、医生和/或患者以前使用某些药物的临床经验以及医生对绝对风险与相对风险的认知。解读。大多数医生在经过复杂、多因素但基本上以患者为中心的决策过程后,优先开具COXIB。