Jelic Sanja, Le Jemtel Thierry H
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, PH 8, Room 840, 630 West 168th St, New York, NY 10032, USA.
Chest. 2006 Oct;130(4):1220-30. doi: 10.1378/chest.130.4.1220.
COPD affects up to one third of patients with chronic heart failure. The coexistence of COPD and chronic heart failure presents clinicians with diagnostic and therapeutic challenges. Measurement of B-type natriuretic peptide plasma levels facilitates the diagnosis of acute dyspnea in patients known to have both COPD and chronic heart failure. Patients with COPD or chronic heart failure have skeletal muscle abnormalities that limit functional capacity independently from primary organ failure. Exercise training reverses skeletal muscle abnormalities in patients with COPD or chronic heart failure and may be particularly indicated in patients with coexistent COPD and chronic heart failure.
慢性阻塞性肺疾病（COPD）影响多达三分之一的慢性心力衰竭患者。COPD与慢性心力衰竭并存给临床医生带来了诊断和治疗方面的挑战。测量B型利钠肽血浆水平有助于诊断已知患有COPD和慢性心力衰竭的患者的急性呼吸困难。COPD或慢性心力衰竭患者存在骨骼肌异常，这独立于原发性器官衰竭限制了功能能力。运动训练可逆转COPD或慢性心力衰竭患者的骨骼肌异常，对于COPD和慢性心力衰竭并存的患者可能特别适用。
