Dey Tania
Advanced Materials Research Institute, University of New Orleans, New Orleans, LA 70148, USA.
J Nanosci Nanotechnol. 2006 Aug;6(8):2479-83. doi: 10.1166/jnn.2006.534.
ATRP (atom transfer radical polymerization) approach was employed to synthesis polymer-coated magnetite nanoparticles. These particles had an average diameter of 7.1 nm and a narrow size distribution. Characterization was performed using various techniques like Transmission Electron Microscopy (TEM), Ultraviolet-Visible spectroscopy (UV-vis), Fourier Transform Infrared spectroscopy (FTIR), Atomic Force Microscopy (AFM), and Vibrating Sample Magnetometry (VSM). The challenge was to obtain a thin shell and discrete particles in an unagglomerated state. Several factors like presence/choice of solvent, monomer-to-initiator concentration and structure of initiator were found to play a key role in this study. Attempts have been made to tailor the polymer shells by end-functionalization. This work has an enormous biomedical application potential.
采用原子转移自由基聚合（ATRP）方法合成了聚合物包覆的磁铁矿纳米颗粒。这些颗粒的平均直径为7.1纳米，尺寸分布狭窄。使用透射电子显微镜（TEM）、紫外可见光谱（UV-vis）、傅里叶变换红外光谱（FTIR）、原子力显微镜（AFM）和振动样品磁强计（VSM）等各种技术进行了表征。挑战在于获得薄壳且处于未团聚状态的离散颗粒。研究发现，诸如溶剂的存在/选择、单体与引发剂的浓度以及引发剂的结构等几个因素在本研究中起着关键作用。已尝试通过末端功能化来定制聚合物壳。这项工作具有巨大的生物医学应用潜力。
