Cheknev S B, Narovlianskiĭ A N, Amchenkova A M, Sorokin A M, Khesin Ia E, Ershov F I
Biull Eksp Biol Med. 1990 Oct;110(10):406-9.
The cytotoxic activity of peripheral blood natural killers (NK) against target cells (TC) J-96 and L-929 with high sensitivity to interferon (IFN) action, J-41 and MCB resistant to IFN action and line K-562 labelled by H3-uridine was studied in 14 hrs cytotoxic test. It has been shown that human TC J-96 didn't differ from the J-41 in their sensitivity to NK cytotoxicity and they are strongly resistant to NK than TC K-562. The murine TC L-929 as the human TC didn't differ from the MCB in their sensitivity to NK lysis and had also the same sensitivity to NK as the K-562 cells.
在14小时细胞毒性试验中，研究了外周血自然杀伤细胞（NK）对高敏干扰素（IFN）作用的靶细胞（TC）J - 96和L - 929、抗IFN作用的J - 41和MCB以及用H3 - 尿苷标记的K - 562细胞系的细胞毒性活性。结果表明，人TC J - 96对NK细胞毒性的敏感性与J - 41无差异，且它们比TC K - 562对NK的抗性更强。与人类TC一样，鼠类TC L - 929对NK裂解的敏感性与MCB无差异，对NK的敏感性也与K - 562细胞相同。
