Razvi S S M, Leach J P
Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow, UK.
Eur J Neurol. 2006 Nov;13(11):1261-3. doi: 10.1111/j.1468-1331.2006.01456.x.
A 43-year-old lady presented with bilateral foot drop due to alcohol-related peripheral neuropathy. There was no history of electrolyte disturbance or altered consciousness. Cranial nerve, bulbar and pyramidal symptoms and signs were absent. Nerve conduction studies confirmed the neuropathy. Inadvertently requested neuroimaging of brain demonstrated signal change typical of central pontine myelinolysis. Asymptomatic pontine myelinolysis occurs rarely in alcoholics in the absence of bulbar dysfunction. It is important for physicians to be aware of the clinical entity of asymptomatic pontine myelinolysis to avoid misinterpretation of abnormalities detected on cerebral imaging in alcoholic individuals.
一名43岁女性因酒精相关性周围神经病出现双侧足下垂。无电解质紊乱或意识改变病史。无颅神经、延髓及锥体束症状和体征。神经传导研究证实了该神经病。无意中进行的脑部神经影像学检查显示出典型的中央桥脑髓鞘溶解的信号改变。在没有延髓功能障碍的情况下，无症状性桥脑髓鞘溶解在酗酒者中很少见。医生了解无症状性桥脑髓鞘溶解这一临床实体很重要，以避免对酗酒个体脑部影像学检查中发现的异常进行错误解读。
