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接受慢性血液透析治疗患者的丙型肝炎病毒抗体(HCV)

[Hepatitis C virus antibodies (HCV) in patients treated with chronic hemodialysis].

作者信息

Kühnl P, Roggendorf M, Sibrowski W, Deinhardt F, Laufs R, Bornhövd K, Kalmar G, Seidl S, Böhm B O

机构信息

Abt. f. Transfusionsmedizin und Transplantationsimmunologie, Universität Hamburg.

出版信息

Beitr Infusionsther. 1990;26:27-9.

PMID:1703848
Abstract

Patients undergoing chronic hemodialysis are frequently affected by nosocomial viral infections, as indicated by the high prevalence of HBV antibodies. The question, to what extent HCV is transmitted by blood transfusions (NANB-PTH), or acquired in a nosocomial manner, is still unanswered. We therefore evaluated the HCV antibody rate of 387 sera of dialysis patients on the "Eurotransplant" waiting list. The HCV antibody reactivity ranged from 5.4 to 12.0% between different dialysis centers. In highly immunized (HLA antibody positive) long-term dialysis patients 31.3% (vs. 8.3% in non-immunized patients) were HCV antibody positive.

摘要

慢性血液透析患者经常受到医院内病毒感染的影响,乙肝病毒抗体的高流行率表明了这一点。丙型肝炎病毒(HCV)在多大程度上通过输血传播(非甲非乙型输血后肝炎),或以医院内感染的方式获得,这个问题仍然没有答案。因此,我们评估了“欧洲移植”等待名单上387名透析患者血清的HCV抗体率。不同透析中心之间的HCV抗体反应性在5.4%至12.0%之间。在高度免疫(HLA抗体阳性)的长期透析患者中,31.3%(非免疫患者为8.3%)的HCV抗体呈阳性。

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