Heim M U, Weidemann R, Brehm G, Versmold H, Mempel W
Transfusionszentrum, Universität München.
Beitr Infusionsther. 1990;26:302-6.
Anti-PP1Pk developed by women has been associated with abortion early in pregnancy and hemolytic disease of the newborn. The case of a 19-year-old woman who had had 2 spontaneous abortions in the first trimester is presented. When treated with plasma exchange and substituted with 5% albumin and intravenous immunoglobulin begun at six weeks' gestation and continued until the 30th week, she delivered a viable female infant without anemia. According to our data and review of literature, the effectiveness of therapy by plasmapheresis and/or immunoglobulin is discussed.
女性产生的抗PP1Pk与妊娠早期流产及新生儿溶血病有关。本文介绍了一名19岁女性的病例，她在孕早期发生了2次自然流产。在妊娠6周开始进行血浆置换，并输注5%白蛋白和静脉注射免疫球蛋白直至第30周，她产下了一名存活的女婴，且无贫血症状。根据我们的数据及文献回顾，讨论了血浆置换和/或免疫球蛋白治疗的有效性。
