Strowitzki T, Wiedemann R, Heim M U, Brehm G, Roithmeier A
Frauenklinik, Klinikum Grosshadern der LMU München.
Geburtshilfe Frauenheilkd. 1991 Sep;51(9):710-3. doi: 10.1055/s-2007-1023820.
The authors report on a successful pregnancy in a young Turkish patient with p and anti-PP1Pk-antibodies. Anti-PP1Pk is considered to cause haemolytic diseases in the newborn and habitual abortions. The patient was treated via plasma exchange and substitution with intravenous immunoglobulin. At 31 weeks of gestation the patient underwent Caesarean section due to growth retardation and pathological signs in the fetal CTG. The child has developed well up to two years after the delivery. Based on our data and a review of the literature, the effectiveness of therapy by plasmapheresis and/or immunoglobulin is discussed.
作者报告了一名年轻的土耳其患者成功怀孕的案例，该患者患有P抗体和抗PP1Pk抗体。抗PP1Pk被认为会导致新生儿溶血病和习惯性流产。该患者接受了血浆置换和静脉注射免疫球蛋白替代治疗。妊娠31周时，由于胎儿生长受限和胎儿CTG出现病理迹象，患者接受了剖宫产。孩子在出生后两年内发育良好。基于我们的数据并结合文献综述，讨论了血浆置换和/或免疫球蛋白治疗的有效性。
