Eliades M James, Wolkon Adam, Morgah Kodjo, Crawford Sara B, Dorkenoo Ameyo, Sodahlon Yao, Hawley William A, Hightower Allen W, Kuile Feiko O Ter, Terlouw Dianne J
Malaria Branch, Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Am J Trop Med Hyg. 2006 Oct;75(4):622-9.
A community-based baseline cross-sectional survey was conducted in three districts in Togo in September 2004 as part of a multidisciplinary evaluation of the impact of the Togo National Integrated Child Health Campaign. During this campaign, long-lasting-insecticide-treated bed nets (LLITNs) were distributed to households with children between 9 months and 5 years of age throughout the country in December 2004. The pre-intervention survey provided baseline malaria and anemia prevalence in children < 5 years of age during peak malaria transmission. Of 2,532 enrolled children from 1,740 households, 62.2% (1,352/2,172) were parasitemic and 84.4% (2,129/2,524) were anemic (hemoglobin < 11 g/dL). Moderate-to-severe anemia (< 8.0 g/dL) was found in 21.7% (543/2,524), with a peak prevalence in children 6-17 months of age and was strongly correlated with parasitemia (OR = 2.3, 95% CI: 1.8-2.5). Net ownership (mainly untreated) was 225/2,532 (8.9%). Subsequent nation-wide introduction of LLITNs and the introduction of artemisinin-based combination therapy have the potential to markedly reduce this burden of malaria.
2004年9月，在多哥的三个地区开展了一项基于社区的基线横断面调查，作为对多哥国家儿童综合健康运动影响进行多学科评估的一部分。在此次运动期间，2004年12月向全国有9个月至5岁儿童的家庭分发了长效驱虫蚊帐。干预前调查提供了疟疾传播高峰期5岁以下儿童的疟疾和贫血患病率基线。在来自1740户家庭的2532名登记儿童中，62.2%（1352/2172）有寄生虫血症，84.4%（2129/2524）贫血（血红蛋白<11g/dL）。21.7%（543/2524）的儿童患有中度至重度贫血（<8.0g/dL），6至17个月龄儿童的患病率最高，且与寄生虫血症密切相关（比值比=2.3，95%置信区间：1.8-2.5）。蚊帐拥有率（主要是未处理蚊帐）为225/2532（8.9%）。随后在全国范围内引入长效驱虫蚊帐以及引入以青蒿素为基础的联合疗法有可能显著减轻这种疟疾负担。
