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筑波假丝酵母中霉菌素的产生

Mycocin production in Pseudozyma tsukubaensis.

作者信息

Golubev Wladyslav I, Pfeiffer Ilona, Golubeva Ellen W

机构信息

Russia Collection of Microorganisms (VKM), Institute for Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, 142290, Russia.

出版信息

Mycopathologia. 2006 Oct;162(4):313-6. doi: 10.1007/s11046-006-0065-2.

Abstract

Killer activity expressed at pH values ranging from 3.5 to 6.0 was found in the ustilaginaceous yeast-like species, Pseudozyma tsukubaensis. Its killer phenotype was incurable, and extrachromosomal genetic elements were not detected. The toxin excreted with a molecular mass above 15 kDa is fungicidal, resistant to proteolytic cleavage, thermolabile and active only against fungi within the Ustilaginomycetes (the orders Microstromatales and Ustilaginales).

摘要

在黑粉菌状酵母样物种筑波假丝酵母(Pseudozyma tsukubaensis)中发现了在pH值3.5至6.0范围内表达的杀伤活性。其杀伤表型无法治愈,且未检测到染色体外遗传元件。分泌出的分子量大于15 kDa的毒素具有杀真菌作用,对蛋白水解切割具有抗性,不耐热,且仅对黑粉菌纲(微座孢目和黑粉菌目)内的真菌有活性。

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