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N100听觉诱发磁场源定位中的性别差异。

Gender differences in source location for the N100 auditory evoked magnetic field.

作者信息

Baumann S B, Rogers R L, Guinto F C, Saydjari C L, Papanicolaou A C, Eisenberg H M

机构信息

Magnetoencephalography Laboratory, University of Texas Medical Branch, Galveston 77550.

出版信息

Electroencephalogr Clin Neurophysiol. 1991 Jan-Feb;80(1):53-9. doi: 10.1016/0168-5597(91)90043-w.

Abstract

Auditory evoked magnetic fields were recorded in response to contralateral stimulation over the right hemisphere in 6 adult males and 6 adult females. The data were fit to a model of a current-dipole source in a homogeneous sphere and 5 parameters of the dipole were computed--3 spatial coordinates, orientation, and strength. When average values for the dipole parameters were compared between sexes, it was found that the current source for the N100m is located more than 1 cm posterior in females and is oriented pointing more downward. These findings were replicated in separate measurement sessions. Viewing of individual magnetic resonance images did not reveal a corresponding anatomical disparity in the location of the primary auditory cortex which is assumed to produce the N100m. Therefore, functional organization of the auditory cortex may be different for the sexes.

摘要

在6名成年男性和6名成年女性中,记录了对右半球对侧刺激的听觉诱发磁场。数据拟合到均匀球体中电流偶极子源的模型,并计算了偶极子的5个参数——3个空间坐标、方向和强度。当比较两性之间偶极子参数的平均值时,发现女性中N100m的电流源位于后方超过1厘米处,且方向更向下。这些发现在单独的测量环节中得到了重复。对个体磁共振图像的观察并未揭示假定产生N100m的初级听觉皮层位置上相应的解剖学差异。因此,听觉皮层的功能组织可能在两性中有所不同。

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