Meydanli M Mutlu, Engin-Ustün Yaprak, Ustün Yusuf, Deniz Denizhan, Temel Ismail, Firat Serpil
Department of Obstetrics and Gynecology, School of Medicine, Inonu University, 44069-Malatya, Turkey.
J Reprod Med. 2006 Sep;51(9):704-8.
To assess the effects of meconium-stained amniotic fluid and umbilical cord plasma motilin levels on the development of infantile colic.
One hundred forty pregnant women referred to our department for labor care were enrolled in the study. All subjects were laboring women with singleton, vertex-presenting fetuses, with a gestational age of > or = 36 weeks. After each infant with meconium-stained amniotic fluid was born, the following 2 infants without meconium were selected as controls. Umbilical cord plasma motilin levels were measured in 47 infants with meconium-stained amniotic fluid and 93 infants with no meconium. At the end of the third month of the infants' lives, the development of infantile colic was evaluated. Umbilical cord serum specimens were collected from 45 infants with colic and 95 infants without colic. Statistics included Student's t, chi2 and Mann-Whitney U tests, as appropriate. Multivariate analysis was performed.
There was no correlation between the presence of meconium-stained amniotic fluid and the development of infantile colic. No association was found between umbilical cord plasma motilin levels and the development of infantile colic. Neonatal intensive care unit admission was found to be a significant risk factor for the development of infantile colic.
Meconium-stained amniotic fluid and umbilical cord plasma motilin levels do not affect the development of infantile colic.
评估胎粪污染羊水及脐带血浆胃动素水平对婴儿腹绞痛发生发展的影响。
140名转诊至我科进行分娩护理的孕妇纳入本研究。所有受试者均为单胎、头先露胎儿的产妇，孕周≥36周。每例胎粪污染羊水的婴儿出生后，选取接下来的2例无胎粪污染的婴儿作为对照。测定47例胎粪污染羊水婴儿和93例无胎粪污染婴儿的脐带血浆胃动素水平。在婴儿出生后第三个月末，评估婴儿腹绞痛的发生情况。收集45例腹绞痛婴儿和95例无腹绞痛婴儿的脐带血清标本。根据情况，统计学分析包括Student's t检验、卡方检验和Mann-Whitney U检验。进行多因素分析。
胎粪污染羊水与婴儿腹绞痛的发生之间无相关性。未发现脐带血浆胃动素水平与婴儿腹绞痛的发生之间存在关联。发现新生儿重症监护病房入院是婴儿腹绞痛发生的一个重要危险因素。
胎粪污染羊水及脐带血浆胃动素水平不影响婴儿腹绞痛的发生发展。
