Grey Benjamin R, Clarke Laurence, Maddineni Satish B, Hunt Roger, Brough Richard J
Department of Urology, Stepping Hill Hospital, Stockport, UK.
BMC Urol. 2006 Oct 14;6:29. doi: 10.1186/1471-2490-6-29.
Primary malignancies of colorectal origin can metastasise to the bladder. Reports are however extremely rare, particularly from the caecum.
The report describes the case of a 45-year old male with Duke's B caecal carcinoma treated with a laparoscopically-assisted right hemicolectomy and adjuvant 5-Fluorouracil chemotherapy. Subsequently, a metastatic lesion to the bladder was demonstrated and successfully excised by partial cystectomy.
In order that optimal therapeutic options can be determined, it is important for clinicians to distinguish between primary disease of the bladder and other causes of haematuria. Various immunohistochemical techniques attempt to differentiate primary adenocarcinoma of the bladder from secondary colorectal adenocarcinoma. Suspicion of metastatic disease must be raised when histologically unusual bladder tumours are identified.
原发性结直肠癌可转移至膀胱。然而，相关报道极为罕见，尤其是来自盲肠的病例。
该报告描述了一名45岁男性，患有杜克B期盲肠癌，接受了腹腔镜辅助右半结肠切除术及辅助性5-氟尿嘧啶化疗。随后，发现膀胱出现转移灶，并通过部分膀胱切除术成功切除。
为了确定最佳治疗方案，临床医生区分膀胱原发性疾病和其他血尿原因非常重要。各种免疫组化技术试图将膀胱原发性腺癌与继发性结肠腺癌区分开来。当发现组织学上不寻常的膀胱肿瘤时，必须怀疑存在转移性疾病。
