Wehman J Christopher, Holmes David R, Hanel Ricardo A, Levy Elad I, Hopkins L Nelson
Department of Neurosurgery and Toshiba Stroke Research Center, University at Buffalo, State University of New York, Buffalo, New York, USA.
Neurosurgery. 2006 Oct;59(4 Suppl 2):ONSE481-3; discussion ONSE483. doi: 10.1227/01.NEU.0000222825.92929.0C.
Intravascular ultrasound (IVUS) imaging has been used extensively in coronary artery interventions and has provided invaluable information for the understanding and treatment of coronary arterial disease. We present here the first description, to our knowledge, of IVUS-guided intracranial arterial interventions in the clinical setting.
Two patients underwent intracranial angioplasty and stent placement with the assistance of IVUS for the evaluation of their lesions. One patient underwent stenting to treat an occlusive dissection of the left internal carotid artery that occurred during arteriovenous malformation embolization. Another patient underwent angioplasty and stenting for high-grade restenosis of a basilar artery atherosclerotic lesion.
Both patients underwent successful revascularization procedures. The patient with the dissection had a small intraventricular and parenchymal hemorrhage documented by computed tomography 4 hours after treatment, but did not develop hydrocephalus or further hemorrhage. Both patients did well clinically and had no permanent neurological deficits. IVUS provided important information in terms of lesion evaluation, stent selection, and stent placement in each case.
IVUS of the intracranial circulation may assist the performance of intracranial angioplasty and stenting. It provides useful information that can affect clinical decisions. It may prove to be a valuable tool in clinical use and enhance our understanding of vascular disease of the intracranial circulation, as it has in the coronary circulation.
血管内超声(IVUS)成像已广泛应用于冠状动脉介入治疗,并为理解和治疗冠状动脉疾病提供了宝贵信息。据我们所知,本文首次描述了在临床环境中IVUS引导下的颅内动脉介入治疗。
两名患者在IVUS辅助下接受了颅内血管成形术和支架置入术以评估其病变。一名患者在动静脉畸形栓塞过程中发生左侧颈内动脉闭塞性夹层,接受了支架置入治疗。另一名患者因基底动脉粥样硬化病变的高度再狭窄接受了血管成形术和支架置入术。
两名患者均成功完成了血运重建手术。夹层患者在治疗后4小时经计算机断层扫描记录有小的脑室内和脑实质出血,但未发生脑积水或进一步出血。两名患者临床情况良好,无永久性神经功能缺损。IVUS在每个病例的病变评估、支架选择和支架置入方面都提供了重要信息。
颅内循环的IVUS可能有助于颅内血管成形术和支架置入术的实施。它提供了可影响临床决策的有用信息。它可能被证明是一种有价值的临床工具,并能增强我们对颅内循环血管疾病的理解,就像它在冠状动脉循环中所起的作用一样。