Karlsson Berit, Berglin Ewa, Wållberg-Jonsson Solveig
Department of Rheumatology, University Hospital, Umeå, Sweden.
Scand J Occup Ther. 2006 Sep;13(3):193-9. doi: 10.1080/11038120500462337.
The aim of this study was to describe life satisfaction prospectively in patients with early rheumatoid arthritis (RA) and to investigate its correlation with disease activity. The early RA group was compared with RA patients with longstanding disease and with a reference group. Gender differences were also compared. Patients with early RA, treated by a multidisciplinary team, reported their life satisfaction by completing a questionnaire. Disease activity score, patient global assessment, and pain were scored at onset of disease and after two years. The patients with early RA were less satisfied with life as a whole at disease onset compared with the reference group, as was a cohort of patients with longstanding disease. Patients with early RA also reported low levels of satisfaction with self-care activities, work, and sexual life. The women reported themselves more satisfied than men. After two years, a slight increase in the reported levels of satisfaction could be seen for life as a whole and for five of the eight domains. No correlation was found between disease activity variables and satisfaction with life as a whole. There were, however, positive correlations between disease activity and satisfaction both with partnership and with family life after two years, i.e. the higher disease activity the higher satisfaction with partnership relation and family life. In contrast, patients with greater disease activity were less satisfied with self-care activities. The results of this study indicate that greater effort is needed to assist patients with early RA to cope with problems concerning self-care activities, sexual life, and work.
本研究旨在前瞻性地描述早期类风湿关节炎（RA）患者的生活满意度，并调查其与疾病活动度的相关性。将早期RA组与病程较长的RA患者以及一个参照组进行比较。还比较了性别差异。由多学科团队治疗的早期RA患者通过填写问卷来报告他们的生活满意度。在疾病发作时和两年后对疾病活动评分、患者整体评估和疼痛进行评分。与参照组相比，早期RA患者在疾病发作时对整体生活的满意度较低，病程较长的患者队列也是如此。早期RA患者对自我护理活动、工作和性生活的满意度也较低。女性报告的满意度高于男性。两年后，整体生活以及八个领域中的五个领域的报告满意度略有增加。未发现疾病活动变量与整体生活满意度之间存在相关性。然而，两年后疾病活动度与伴侣关系和家庭生活满意度之间存在正相关，即疾病活动度越高，对伴侣关系和家庭生活的满意度越高。相比之下，疾病活动度较高的患者对自我护理活动的满意度较低。本研究结果表明，需要付出更大努力来帮助早期RA患者应对自我护理活动、性生活和工作方面的问题。
