Chollet Guillaume, Guillerez Marie-George, Schulz Emmanuelle
Equipe de Catalyse Moléculaire, ICMMO, UMR 8182, Université Paris-Sud, 91405 Orsay, France.
Chemistry. 2007;13(3):992-1000. doi: 10.1002/chem.200601081.
A new method for recycling chiral bis(oxazoline)-copper complexes is described based on the formation of charge-transfer complexes, their subsequent precipitation, and reuse after addition of new substrates. The conditions to perform this procedure were optimized in the presence of three bis(oxazoline)-based ligands. When associated with copper salts, these ligands efficiently catalyzed the Diels-Alder reaction between cyclopentadiene and alpha,beta-unsaturated acyloxazolidinones. These catalysts were successfully recycled up to ten times while maintaining their high activities and enantioselectivities.
本文描述了一种回收手性双（恶唑啉）-铜配合物的新方法，该方法基于电荷转移配合物的形成、随后的沉淀以及添加新底物后的再利用。在三种基于双（恶唑啉）的配体存在下，对进行该过程的条件进行了优化。当与铜盐结合时，这些配体有效地催化了环戊二烯与α，β-不饱和酰基恶唑烷酮之间的狄尔斯-阿尔德反应。这些催化剂成功地循环使用了多达十次，同时保持了高活性和对映选择性。
