形态发生的三维模拟框架。
A framework for three-dimensional simulation of morphogenesis.
作者信息
Cickovski Trevor M, Huang Chenbang, Chaturvedi Rajiv, Glimm Tilmann, Hentschel H George E, Alber Mark S, Glazier James A, Newman Stuart A, Izaguirre Jesús A
机构信息
Laboratory for Computational Life Sciences, Department of Computer Science and Engineering, University of Notre Dame, 325 Cushing Hall, Notre Dame, IN 46556, USA.
出版信息
IEEE/ACM Trans Comput Biol Bioinform. 2005 Oct-Dec;2(4):273-88. doi: 10.1109/TCBB.2005.46.
We present COMPUCELL3D, a software framework for three-dimensional simulation of morphogenesis in different organisms. COMPUCELL3D employs biologically relevant models for cell clustering, growth, and interaction with chemical fields. COMPUCELL3D uses design patterns for speed, efficient memory management, extensibility, and flexibility to allow an almost unlimited variety of simulations. We have verified COMPUCELL3D by building a model of growth and skeletal pattern formation in the avian (chicken) limb bud. Binaries and source code are available, along with documentation and input files for sample simulations, at http:// compucell.sourceforge.net.
我们展示了COMPUCELL3D，这是一个用于不同生物体形态发生三维模拟的软件框架。COMPUCELL3D采用与生物学相关的模型来进行细胞聚类、生长以及与化学场的相互作用。COMPUCELL3D使用设计模式来实现速度、高效内存管理、可扩展性和灵活性，以允许进行几乎无限多种模拟。我们通过构建鸟类（鸡）肢体芽生长和骨骼模式形成的模型来验证了COMPUCELL3D。二进制文件、源代码以及样本模拟的文档和输入文件可在http://compucell.sourceforge.net获取。
Zotero 插件