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[肺癌患者红细胞的功能特性]

[Functional characteristics of the erythrocytes in patients with lung cancer].

作者信息

Stepovaia E A, Gol'dberg V E, Novitskiĭ V V

出版信息

Lab Delo. 1990(10):51-3.

PMID:1704460
Abstract

Peripheral blood red cells were studied in 35 newly detected (untreated) male patients with Stages III-IV lung cancer by cytophotometric (sulfhydryl groups, lipoproteins) and interferometric (dry mass) techniques. The reference groups included patients with chronic nonspecific pulmonary diseases (CNPD) and healthy volunteers. The findings evidence that sulfhydryl group, lipoprotein concentrations and dry mass mean values of red cells are significantly lower in lung cancer patients than those in both reference groups. The changes detected in CNPD patients are similar to those in lung cancer patients but are less manifest.

摘要

采用细胞光度法(巯基、脂蛋白)和干涉测量法(干质量)技术,对35例新确诊(未治疗)的Ⅲ - Ⅳ期肺癌男性患者的外周血红细胞进行了研究。参照组包括慢性非特异性肺部疾病(CNPD)患者和健康志愿者。研究结果表明,肺癌患者红细胞的巯基、脂蛋白浓度和干质量平均值显著低于两个参照组。CNPD患者检测到的变化与肺癌患者相似,但程度较轻。

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