El Sayed Fouad, Dhaybi Rola, Ammoury Alfred, El Haddad Boutros, Bazex Jacques
Division de Dermatologie, Faculté de Médecine, Université Libanaise, Beyrouth, Liban.
J Med Liban. 2006 Jan-Mar;54(1):28-31.
Bazex syndrome or acrokeratosis paraneoplastica is a rare dermatosis usually associated with a squamous cell carcinoma of upper aerodigestive tract or with metastases in the cervical lymph nodes. It presents as psoriasiform violaceous scaly patches over extremities, tip of the nose, earlobes and helices. This syndrome evolves in three stages parallel to the growth of the tumor, thus the utility of recognition of the syndrome which may unmask the associated neoplasia at an early stage. Treatment consists of treating the underlying neoplasia whether by surgery, chemotherapy and/or radiotherapy. Recurrence of cutaneous lesions may reveal the recurrence of the tumor.
巴泽克斯综合征或副肿瘤性肢端角化病是一种罕见的皮肤病,通常与上消化道鳞状细胞癌或颈部淋巴结转移有关。其表现为四肢、鼻尖、耳垂和耳轮上出现银屑病样紫蓝色鳞屑斑。该综合征与肿瘤的生长平行发展为三个阶段,因此识别该综合征有助于在早期发现相关肿瘤。治疗包括通过手术、化疗和/或放疗治疗潜在的肿瘤。皮肤病变的复发可能提示肿瘤复发。