Landman M A, Senden P J, van Rooijen H, van Hemel N M
Eemland Hospital, Amersfoort, The Netherlands.
Pacing Clin Electrophysiol. 1990 Dec;13(12 Pt 1):1615-22. doi: 10.1111/j.1540-8159.1990.tb06863.x.
In the rate adaptive pacemakers, all presently available sensors show one or more drawbacks. Combining two sensors in a single pacemaker, we tried to optimize its rate responsive characteristics. In this study, we present the rate adaptive behavior of a two sensor pacemaker system, using both QT interval and activity sensing. In addition, we compared the rate response with that of each sensor alone. Nine patients with an implanted QT interval sensing pacemaker, and an externally attached activity sensing pacemaker performed three exercise stress tests on treadmill. The QT interval, measured by the implanted pacemaker, and the activity level, were transmitted to an external computer. This computer contained the two sensor rate adaptive algorithm, and reprogrammed the implanted pacemaker on beat-to-beat basis.
In the two sensor mode the rate increases immediately at the onset of exercise, caused by the prompt response of the activity sensor. Further rate increase is driven by the QT interval sensor and therefore proportional to the level of exercise. Furthermore, the rate decay during the recovery phase is more physiological.
在频率适应性起搏器中,目前所有可用的传感器都存在一个或多个缺点。我们尝试在单个起搏器中结合两个传感器,以优化其频率响应特性。在本研究中,我们展示了一个使用QT间期和活动感知的双传感器起搏器系统的频率适应性行为。此外,我们将该频率响应与每个单独传感器的频率响应进行了比较。九名植入了QT间期感知起搏器且外部连接了活动感知起搏器的患者在跑步机上进行了三次运动应激测试。由植入式起搏器测量的QT间期和活动水平被传输到一台外部计算机。这台计算机包含双传感器频率自适应算法,并逐搏重新编程植入式起搏器。
在双传感器模式下,由于活动传感器的快速响应,运动开始时频率立即增加。进一步的频率增加由QT间期传感器驱动,因此与运动水平成正比。此外,恢复阶段的频率下降更符合生理情况。