Dominguez-Rodriguez Alberto, Garcia-Gonzalez Martin, Abreu-Gonzalez Pedro
Int J Cardiol. 2007 Jul 10;119(2):227-9. doi: 10.1016/j.ijcard.2006.07.110. Epub 2006 Oct 12.
A circadian variation in the time of onset of ST-segment elevation myocardial infarction (STEMI) with peak in the morning hours has been described. We sought to investigate the impact of circadian patterns on the practice of primary angioplasty in individuals residing in Tenerife Island (Spain).
90 consecutive patients with STEMI were treated in our hospital. All patients were admitted within 6 h from symptom onset. Patients were divided into 2 groups according to the time of treatment: routine duty hours (0800-1800) and off-hours (1800-0800).
There were no differences in baseline clinical characteristics or treatment delays between routine duty hours and off-hours patients. There is a significant higher rate of angioplasty failure and in-hospital mortality from 1800 to 0800 h compared to the time range from 0800 to 1800 h.
Circadian variations have a profound effect on the practice of primary angioplasty.
已有描述指出,ST 段抬高型心肌梗死(STEMI)发病时间存在昼夜节律变化,早晨时段达到高峰。我们试图研究昼夜节律模式对居住在西班牙特内里费岛个体的直接经皮冠状动脉腔内血管成形术(primary angioplasty)操作的影响。
我们医院连续治疗了 90 例 STEMI 患者。所有患者均在症状发作后 6 小时内入院。根据治疗时间将患者分为两组:常规值班时间(08:00 - 18:00)和非值班时间(18:00 - 08:00)。
常规值班时间组和非值班时间组患者的基线临床特征或治疗延迟方面无差异。与 08:00 至 18:00 时间段相比,18:00 至 08:00 时段血管成形术失败率和院内死亡率显著更高。
昼夜节律变化对直接经皮冠状动脉腔内血管成形术操作有深远影响。