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足月缺氧缺血性脑病患儿心肌功能与脑血流动力学的相关性

The correlation between myocardial function and cerebral hemodynamics in term infants with hypoxic-ischemic encephalopathy.

作者信息

Liu Jing, Li Jian, Gu Mei

机构信息

Department of Neonatology, Beijing Obstetrics and Gynecology Hospital Affiliated to Capital University of Medical Science, Beijing, China.

出版信息

J Trop Pediatr. 2007 Feb;53(1):44-8. doi: 10.1093/tropej/fml053. Epub 2006 Oct 17.

Abstract

This study investigated the effect of myocardial dysfunction on the cerebral hemodynamics in term infants with hypoxic-ischemic encephalopathy (HIE). We evaluated myocardial systolic and diastolic functional parameters and cerebral hemodynamic parameters in 40 term newborn infants with HIE and 30 healthy controls during the first 14 days of life using two-dimensional/pulsed Doppler ultrasound. The results showed that there were significant cerebral hemodynamic disturbances and cardiac dysfunction in neonates with HIE, and the more cardiac dysfunction the patients have, the more severe encephalopathy they would suffer. Therefore, it is important to preserve cardiac function and treat myocardial dysfunction in infants with HIE.

摘要

本研究调查了心肌功能障碍对足月新生儿缺氧缺血性脑病(HIE)患儿脑血流动力学的影响。我们在出生后的前14天内,使用二维/脉冲多普勒超声评估了40例足月HIE新生儿和30例健康对照者的心肌收缩和舒张功能参数以及脑血流动力学参数。结果显示,HIE新生儿存在明显的脑血流动力学紊乱和心脏功能障碍,且心脏功能障碍越严重,患儿患脑病的程度就越重。因此,保护HIE患儿的心脏功能并治疗心肌功能障碍具有重要意义。

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