O'Grady J G
Institute of Liver Studies, King's College Hospital, Denmark Hill, London SE5 9RS, UK. john.o'
Gut. 2006 Nov;55(11):1529-31. doi: 10.1136/gut.2005.090506.
Outcomes after liver transplantation for alcohol related liver disease compare very favourably with those documented for other causes of cirrhosis. Despite this, 5% or less of patients with advanced alcohol related liver disease are considered for transplantation. The reasons for this are complex but include professional reluctance to refer these patients for formal assessment as well as a limited and dwindling number of organs available for transplantation. Demonstrating abstinence from alcohol consumption remains central to the assessment of candidates for transplantation. Return to alcohol consumption after transplantation can follow a pattern of abuse with consequences for health and survival but may also be controlled and of little clinical significance. A better understanding of the issues influencing these outcomes should decrease the tension that currently exists between patient expectations, professional opinion, and the attitude of the general public who gift organs for donation.
酒精性肝病肝移植后的结果与其他肝硬化病因的记录结果相比非常有利。尽管如此，晚期酒精性肝病患者中只有5%或更少的人被考虑进行移植。原因很复杂，包括专业人员不愿将这些患者转介进行正式评估，以及可用于移植的器官数量有限且不断减少。证明戒酒仍然是评估移植候选人的核心。移植后恢复饮酒可能会出现滥用模式，对健康和生存产生影响，但也可能得到控制且临床意义不大。更好地理解影响这些结果的问题，应该会减少目前患者期望、专业意见和捐赠器官的公众态度之间存在的紧张关系。
