Domnitskaia T M, Sidorenko B A, Erokhina M G, Saidova M A
Kardiologiia. 2006;46(8):63-8.
Non-compaction of the left ventricle or spongy myocardium is a rare congenital cardiomyopathy which is characterized by impaired endomyocardial morphogenesis, hypertrophy of left ventricular myocardium with prominent trabeculation, and deep inter-trabecular recesses. According to WHO classification (1995) this disease belongs to unclassified cardiomyopathies. Main clinical signs of ventricular non-compaction are heart failure, ventricular arrhythmias, systemic and pulmonary embolism. Echocardiography which is a basic method of diagnosis can reveal double layer structure of thickened left ventricular wall and multiple prominent trabeculation with wide inter-trabecular spaces. Predominant localizations of pathological process are region of cardiac apex, inferior and lateral left ventricular walls. Treatment of patients with ventricular non-compaction concentrates on elimination of its main clinical symptoms.
左心室心肌致密化不全或海绵状心肌是一种罕见的先天性心肌病，其特征为心内膜形态发生受损、左心室心肌肥厚伴明显的肌小梁形成以及肌小梁间深陷。根据世界卫生组织1995年的分类，该病属于未分类的心肌病。心室心肌致密化不全的主要临床症状为心力衰竭、室性心律失常、全身和肺栓塞。超声心动图作为基本的诊断方法，可显示增厚的左心室壁的双层结构以及多个突出的肌小梁和较宽的肌小梁间隙。病理过程的主要定位是心尖区域、左心室下壁和侧壁。心室心肌致密化不全患者的治疗集中于消除其主要临床症状。
