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慢性肾衰竭患儿的精神障碍

Psychiatric disorders in children with chronic renal failure.

作者信息

Bakr Ashraf, Amr Mostafa, Sarhan Amr, Hammad Ayman, Ragab Mohamed, El-Refaey Ahmed, El-Mougy Atef

机构信息

Nephrology unit, Mansoura University Children's Hospital, Mansoura, Egypt.

出版信息

Pediatr Nephrol. 2007 Jan;22(1):128-31. doi: 10.1007/s00467-006-0298-9. Epub 2006 Sep 19.

Abstract

Psychiatric assessment was done according to the DSM-IV TR criteria in 19 children with predialysis chronic renal failure (CRF) and 19 children with end-stage renal disease on regular hemodialysis. The prevalence rate of psychiatric disorders in all the studied patients was 52.6%. Adjustment disorders were the most common disorders (18.4%), followed by depression (10.3%) and neurocognitive disorders (7.7%). Anxiety and elimination disorders were reported in 5.1 and 2.6%, respectively. The disorders were more prevalent (P=0.05) in dialysis (68.4%) than in predialysis patients (36.8%). The presence of psychiatric disorders was not significantly correlated with sex, severity of anemia, duration of CRF or the efficiency or the duration of hemodialysis. In conclusion, psychiatric disorders were prevalent in our patients, especially in those on hemodialysis. Both adjustments with depression and depressive disorders were the most common psychiatric disorders. This array of disorders was more likely explained by the difficulties encountered in living with CRF rather than by demographic or physical factors.

摘要

根据《精神疾病诊断与统计手册》第四版修订版(DSM-IV TR)标准,对19例透析前慢性肾衰竭(CRF)患儿和19例接受定期血液透析的终末期肾病患儿进行了精神评估。所有研究患者中精神障碍的患病率为52.6%。适应性障碍是最常见的障碍(18.4%),其次是抑郁症(10.3%)和神经认知障碍(7.7%)。焦虑症和排泄障碍的报告率分别为5.1%和2.6%。这些障碍在透析患者中(68.4%)比透析前患者中(36.8%)更为普遍(P=0.05)。精神障碍的存在与性别、贫血严重程度、CRF病程或血液透析的效率及持续时间均无显著相关性。总之,精神障碍在我们的患者中很普遍,尤其是在接受血液透析的患者中。适应性障碍伴抑郁症和抑郁症是最常见的精神障碍。这一系列障碍更可能是由CRF患者在生活中遇到的困难所致,而非人口统计学或身体因素。

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