Bonde Christian T, Holstein-Rathlou Niels-Henrik, Elberg Jens J
Department of Plastic Surgery and Treatment of Burns, Center of Hand and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
J Reconstr Microsurg. 2006 Oct;22(7):519-24. doi: 10.1055/s-2006-951317.
The objective of this study was to validate a prototype transit time ultrasound flow probe (Medi-Stim Butterfly Flowmeter BF 2004) of only 1 mm and to evaluate its potential for use in microsurgery. Knowledge of the ability of this kind of system to measure flow in small vessels and at small flow rates did not previously exist. The experimental design was an in vitro study using the median artery of 15-kg pigs. The vessel was perfused by the pigs' own heparinated blood, at a known flow rate, using a Gemini infusion pump. The infusion rate was increased stepwise, starting at 1 ml/min until 16 ml/min. Transit time flow was measured continuously. The results showed very accurate flow measurements at all flow rates when compared to the known infusion rate of the Gemini pump. However, at flow rates below 4 ml/min, variation became a problem.
本研究的目的是验证一款仅1毫米的原型经渡越时间超声血流探头（美迪声蝴蝶流量计BF 2004），并评估其在显微外科手术中的应用潜力。此前并不了解这类系统测量小血管内小流量的能力。实验设计为一项体外研究，使用15千克猪的正中动脉。通过Gemini输液泵，以已知流速用猪自身经肝素化处理的血液灌注该血管。输液速率从1毫升/分钟逐步增加至16毫升/分钟。持续测量经渡越时间血流。结果显示，与Gemini泵已知的输液速率相比，在所有流速下血流测量都非常准确。然而，在流速低于4毫升/分钟时，测量值的变化成为一个问题。
