Zhang Jian-feng, Li You-bin, Li Cheng-lu, Jiang Jian-qin
Department of Pharmacy, China Pharmaceutical University, Nanjing 210028, China.
Zhongguo Zhong Yao Za Zhi. 2006 May;31(10):814-6.
To study chemical constituents from Cynanchum auriculatum.
The chemical components were isolated and purified by silca gel, sephedex-LH-20 and ODS column chromatography. The chemical structures were elucidated on the basis of physicochemical properties and spectral data.
Thirteen compounds were isolated and identified as: caudatin (1), metaplexigenin (2), cynauricuoside A (3), succinic acid (4), azelaic acid (5), wilforibiose (6), sucrose (7), 1-O-hexadecanolenin (8), beta-amyrin acetate (9), cynanchone A (10), acetylquinol (11), beta-sitosterol (12), daucosterol (13).
Compounds 4-9 were obtained from this plant for the first time.
研究耳叶牛皮消的化学成分。
采用硅胶柱色谱、葡聚糖凝胶LH-20柱色谱和ODS柱色谱对化学成分进行分离纯化，并根据理化性质和光谱数据对化学结构进行鉴定。
分离鉴定了13个化合物，分别为：考达定（1）、美托孕烯醇（2）、耳叶牛皮消苷A（3）、琥珀酸（4）、壬二酸（5）、隔山消糖（6）、蔗糖（7）、1-O-十六碳烯醇（8）、β-香树脂醇乙酸酯（9）、牛皮消酮A（10）、乙酰喹诺酮（11）、β-谷甾醇（12）、胡萝卜苷（13）。
化合物4-9首次从该植物中获得。
