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[大理白前化学成分的研究]

[Studies on chemical constituents of Cynanchum forrestii].

作者信息

Liu Yue, Liu Jing, Yu Shi-Shan, Huang Xiang-Zhong, Hu You-Cai

机构信息

Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2007 Mar;32(6):500-3.

PMID:17552154
Abstract

OBJECTIVE

To study the chemical constituents of Cynanchum forrestii.

METHOD

Chromatographic techniques were applied to isolated chemical constituents. The structures were identified on the basis of physico-chemical constants and spectroscopic data.

RESULT

Eight compounds were isolated from the 95% ethanol extract of the roots of C. forrestii and elucidated as ( + ) -5'-methoxyisolariciresinol 3a-O-beta-D-glucopyranoside (1), hexahydroxycholest-7-en-6-one (2), tylophorinidine (3), sucrose (4), palmitic acid (5), beta-sitosterol (6), daucosterol (7), nonanedioic acid (8).

CONCLUSION

Compounds 1-3 from this genus, and compounds 4-8 from the plant were obtained for the first time.

摘要

目的

研究大理白前的化学成分。

方法

采用色谱技术分离化学成分。根据理化常数和光谱数据鉴定结构。

结果

从大理白前根的95%乙醇提取物中分离得到8个化合物,分别鉴定为(+)-5'-甲氧基异落叶松脂醇3a-O-β-D-吡喃葡萄糖苷(1)、六羟基胆甾-7-烯-6-酮(2)、娃儿藤定碱(3)、蔗糖(4)、棕榈酸(5)、β-谷甾醇(6)、胡萝卜苷(7)、壬二酸(8)。

结论

化合物1 - 3为本属首次得到,化合物4 - 8为该植物首次得到。

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