Chowdhury A R, Gautam A K
National Institute of Occupational Health, Meghani Nagar, Ahmedabad.
Indian J Physiol Pharmacol. 1990 Jul;34(3):215-7.
Benzene hexachloride (BHC) was fed to mature male rats weighing 160 g at dosages of 3 and 6 mg/kg body weight over a period of 180 days. Significant decrease in testicular weight and degeneration of seminiferous tubules with deformed spermatogenic cells were noted at a dose of 6 mg/kg BHC. Marked increase in BHC residue in testis revealed that the drug was able to cross blood-testis barrier.
