Helbling Josef, Ajdacic-Gross Vladeta, Lauber Christoph, Weyermann Ruth, Burns Tom, Rössler Wulf
Research Unit for Clinical and Social Psychiatry, Psychiatric University Hospital, Zurich, Switzerland.
BMC Psychiatry. 2006 Oct 18;6:42. doi: 10.1186/1471-244X-6-42.
Attitudes towards antipsychotic medication play an important part in the treatment for schizophrenia and related disorders. We aimed measuring general practitioners' attitudes to antipsychotic drugs and their adverse side effects and comparing these with the attitudes of the general population.
Analysis and comparison of two representative samples, one comprising 100 General Practitioners (GPs), the other 791 individuals randomly selected from the general population. The setting was the German speaking cantons of Switzerland.
General practitioners have significantly more positive attitudes towards anti-psychotic drugs than the general public. They reject widespread prejudices about the use of anti-psychotic medication significantly more than the general population. In particular the risk of dependency was assessed as 'low' by GP's (80%), in contrast to only 18% of the general population sample. In no instance did a majority of the GPs advise not tolerating any of the 10 possible adverse effects presented in this study. This is in marked contrast to the general population sample, where a majority recommended discontinuation for movement disorder (63%), strong tremor (59%), risk of dependency (55%) and feelings of unrest (54%).
As well as effective management of side-effects being a vital aspect of patient and carer education, prescribing doctors need to be aware that their mentally ill patients are likely to be confronted with extremely negative public attitudes towards antipsychotic medication and with strong pressures to stop taking their medication in the event of side-effects.
对抗精神病药物的态度在精神分裂症及相关疾病的治疗中起着重要作用。我们旨在衡量全科医生对抗精神病药物及其副作用的态度，并将其与普通人群的态度进行比较。
对两个代表性样本进行分析和比较，一个样本包括100名全科医生（GPs），另一个样本是从普通人群中随机选取的791人。研究地点为瑞士讲德语的州。
全科医生对抗精神病药物的态度明显比普通公众更为积极。他们比普通人群更能显著地摒弃关于使用抗精神病药物的普遍偏见。特别是，全科医生中有80%认为成瘾风险“低”，而普通人群样本中只有18%持此观点。在本研究列出的10种可能的副作用中，没有一种情况是大多数全科医生建议不能耐受的。这与普通人群样本形成鲜明对比，在普通人群样本中，大多数人建议在出现运动障碍（63%）、强烈震颤（59%）、成瘾风险（55%）和不安情绪（54%）时停药。
除了有效管理副作用是患者和护理人员教育的一个重要方面外，开处方的医生需要意识到，他们的精神病患者可能会面临公众对抗精神病药物极其负面的态度，以及在出现副作用时停药的巨大压力。
