Chance S A, Casanova M F, Switala A E, Crow T J
Department of Neuropathology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK.
Neuroscience. 2006 Dec 28;143(4):1041-50. doi: 10.1016/j.neuroscience.2006.08.057. Epub 2006 Oct 16.
To investigate the cytoarchitectural basis of asymmetries in human auditory cortex. Minicolumn spacing and number, and regional cortical volume and surface area were measured in the primary auditory region (Heschl's gyrus, HG) and posterior auditory association region (planum temporale, PT) in 17 neurologically normal adults (10 female, seven male). PT surface area, minicolumn spacing and minicolumn number were greater in the left hemisphere. HG surface area was larger in the left hemisphere. Asymmetries of minicolumn number in primary and association auditory regions correlated with axonal fiber numbers in the subregions of the corpus callosum through which they project. PT minicolumn number was more asymmetrical in men than women but total number was similar in the two sexes. We conclude that asymmetry of the surface area of the PT is a function of minicolumn spacing. Fewer callosal projections between the plana are found when the minicolumn spacing is more asymmetrical.
为研究人类听觉皮层不对称性的细胞构筑基础。对17名神经功能正常的成年人（10名女性，7名男性）的初级听觉区（颞横回，HG）和后听觉联合区（颞平面，PT）的微柱间距和数量、区域皮质体积和表面积进行了测量。PT的表面积、微柱间距和微柱数量在左半球更大。HG的表面积在左半球更大。初级和联合听觉区微柱数量的不对称性与它们投射所经过的胼胝体亚区域的轴突纤维数量相关。男性PT微柱数量的不对称性比女性更明显，但两性的总数相似。我们得出结论，PT表面积的不对称是微柱间距的函数。当微柱间距更不对称时，两侧颞平面之间的胼胝体投射较少。
