Asil Talip, Balci Kemal, Uzunca Ilkay, Kerimoglu Mahmut, Utku Ufuk
Department of Neurology, University of Trakya, 22030 Edirne, Turkey.
J Clin Neurosci. 2006 Nov;13(9):913-6. doi: 10.1016/j.jocn.2006.01.043. Epub 2006 Oct 16.
Ischaemic stroke due to intracranial atherosclerosis is estimated to comprise 8-12% of all ischaemic strokes. It is known that the risk of recurrence is extremely high in patients with ischaemic stroke caused by intracranial stenosis. In the present study we aimed to evaluate the clinical and radiological findings over a 6-month follow-up period in patients with intracranial atherosclerosis. Prospective data for the ischaemic stroke patients admitted to our clinic between 2001 and 2004 were collected. The localization of stenosis/occlusion detected by magnetic resonance angiography (MRA) was recorded and patients were divided into two groups according to the presence of one or more arterial stenoses on MRA. The patients were followed up for 6 months at regular intervals and stroke recurrence and deaths were noted. Of the 47 patients, 11 had posterior circulation stenosis and 36 had anterior circulation stenosis. Thirty-three patients had only one intracranial artery stenosis, whereas 14 had more than one intracranial artery stenosis. Of the 38 patients who completed the 6-month follow-up period, 13 had recurrent stroke, and 10 died. The rate of stroke recurrence in patients with intracranial artery stenosis may be higher than in patients with stroke due to other aetiologies, and stenosis of multiple intracranial arteries increases the rate of recurrence.
颅内动脉粥样硬化所致缺血性卒中估计占所有缺血性卒中的8 - 12%。已知颅内狭窄所致缺血性卒中患者的复发风险极高。在本研究中，我们旨在评估颅内动脉粥样硬化患者在6个月随访期内的临床和影像学表现。收集了2001年至2004年期间入住我们诊所的缺血性卒中患者的前瞻性数据。记录磁共振血管造影（MRA）检测到的狭窄/闭塞部位，并根据MRA上是否存在一处或多处动脉狭窄将患者分为两组。对患者进行定期随访6个月，记录卒中复发情况和死亡情况。47例患者中，11例有后循环狭窄，36例有前循环狭窄。33例患者仅有一处颅内动脉狭窄，而14例有一处以上颅内动脉狭窄。在完成6个月随访期的38例患者中，13例发生复发性卒中，10例死亡。颅内动脉狭窄患者的卒中复发率可能高于其他病因所致卒中患者，多处颅内动脉狭窄会增加复发率。
