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[A群链球菌脂磷壁酸免疫血清的制备]

[Preparation of immune sera to group A streptococcus lipoteichoic acid].

作者信息

Dmitrieva N F, Vylegzhanina E S, Grabovskaia K B, Totolian A A, Blinnikova E I, Briko N I

出版信息

Lab Delo. 1990(11):72-4.

PMID:1704969
Abstract

A method is described for the preparation of sera highly active in reactions with Group A Streptococcus lipoteichoic acid. Ultrasound-destroyed biomass of Streptomyces levoris K-3053 strain is used as the antigen. This strain was isolated in studies of soil Streptomyces; it contains sufficient amounts of nonglycosylated glycerolteichoic acid of the first-third types, that is identical in structure to polyglycerophosphate skeleton of Group A Streptococcus lipoteichoic acid.

摘要

描述了一种制备与A组链球菌脂磷壁酸反应具有高活性血清的方法。将左旋链霉菌K-3053菌株经超声处理破坏的生物质用作抗原。该菌株是在土壤链霉菌研究中分离得到的;它含有足够量的第一至第三类型的非糖基化甘油磷壁酸,其结构与A组链球菌脂磷壁酸的聚甘油磷酸骨架相同。

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