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链球菌脂磷壁酸对替代补体途径的激活。

Activation of the alternative complement pathway by a streptococcal lipoteichoic acid.

作者信息

Fiedel B A, Jackson R W

出版信息

Infect Immun. 1978 Oct;22(1):286-7. doi: 10.1128/iai.22.1.286-287.1978.

Abstract

A glycerol lipoteichoic acid antigen from Streptococcus pyogenes 1-RP41 was found by rabbit erythrocyte hemolytic assay to activate the alternative complement pathway in human sera. Over a narrow concentration range of the teichoic acid, complement consumption was dose dependent, whereas at higher concentrations of the acid complement consumption could not be detected.

摘要

通过兔红细胞溶血试验发现,来自化脓性链球菌1-RP41的甘油脂磷壁酸抗原可激活人血清中的替代补体途径。在脂磷壁酸的狭窄浓度范围内,补体消耗呈剂量依赖性,而在该酸的较高浓度下则检测不到补体消耗。

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