Mertz D P, Hohneck A
Med Klin. 1975 Jul 11;70(28-29):1209-13.
It is reported of 726 patients incidentally elected and mainly with life-shortening risk factors. 341 (47.1p.c.) showed an increased concentration of neutral fats and/or total cholesterol in the serum. Type IV (49.8 p.c.) according to Fredrickson was observed most frequently, followed by type IIb (31.1 p.c.) and by type IIa (19.1 p.c.). Most of the patients with hyperlipoproteinemia were overweight (53.1 p.c.), 33.6 p.c. suffered from arterial hypertension, 25.3 p.c. from diseases of the liver, 10.9 p.c. from coronary heart diseases, and 8.7 p.c. from manifest diabetes mellitus. The distribution of different types of hyperlipoproteinemia among the various diseases deviates from that of the total number of patients observed in this study. Cases of hyperlipoproteinemia were observed most frequently in diseases of the kidney with arterial hypertension (62.7 p.c.), coronary heart diseases (60.8 p.c.), manifest gout (60.0 p.c.), manifest diabetes mellitus (58.7 p.c.), and hyperuricemia without symptoms (55.8 p.c.). Type-IV-hyperlipoproteinemia was observed most frequently within the different groups of patients with life-shortening risk factors. An exception was the group of patients suffering from malignancies. Type IIb was found most frequently within the group of patients suffering from malignancies.
据报道，对726例偶然入选且主要伴有缩短寿命风险因素的患者进行了研究。341例（47.1%）血清中中性脂肪和/或总胆固醇浓度升高。最常观察到的是弗雷德里克森分类法中的IV型（49.8%），其次是IIb型（31.1%）和IIa型（19.1%）。大多数高脂血症患者超重（53.1%），33.6%患有动脉高血压，25.3%患有肝脏疾病，10.9%患有冠心病，8.7%患有显性糖尿病。不同类型高脂血症在各种疾病中的分布与本研究中观察到的患者总数的分布有所不同。高脂血症病例在伴有动脉高血压的肾脏疾病（62.7%）、冠心病（60.8%）、显性痛风（60.0%）、显性糖尿病（58.7%）和无症状高尿酸血症（55.8%）中最为常见。IV型高脂血症在伴有缩短寿命风险因素的不同患者组中最常观察到。患有恶性肿瘤的患者组是个例外。IIb型在患有恶性肿瘤的患者组中最常发现。
