Thomsen Lisbeth E, Knudsen Knud Erik Bach, Jensen Tim K, Christensen Anja S, Møller Kristian, Roepstorff Allan
Danish Centre for Experimental Parasitology, Department of Veterinary Pathobiology, KVL, Dyrlaegevej 100, DK-1870 Frederiksberg C, Denmark.
Vet Microbiol. 2007 Jan 31;119(2-4):152-63. doi: 10.1016/j.vetmic.2006.09.004. Epub 2006 Oct 17.
An experiment was conducted to study the effect of diets with contrasting fermentability in the large intestine on experimental infections with Brachyspira hyodysenteriae, the causative agent of swine dysentery, and the whip worm, Trichuris suis, in pigs. Two diets with organically grown ingredients were composed. Both diets were based on triticale and barley and supplemented with either rape seed cake (Diet 1) or dried chicory root and sweet lupins (Diet 2). The study had a three-factorial design, with eight groups of pigs receiving Diet 1 or Diet 2, +/-B. hyodysenteriae, and +/-T. suis. Pigs fed Diet 2 and challenged with B. hyodysenteriae did not develop swine dysentery and B. hyodysenteriae was not demonstrated in any of the pigs during the study. In contrast, 94% of the B. hyodysenteriae challenged pigs fed Diet 1 showed clinical symptoms of swine dysentery and all the pigs were shedding B. hyodysenteriae in faeces at some points in time during the experiment. The number of T. suis was lower in pigs fed Diet 2 compared to pigs fed Diet 1, but the differences were not significant. Pigs on Diet 1 and challenged with both pathogens showed clinical symptoms of SD for a longer period than pigs inoculated with B. hyodysenteriae only. The study showed that diets supplemented with highly fermentable carbohydrates from dried chicory roots and sweet lupins can protect pigs against developing swine dysentery, but do not have any significant influence on T. suis.
进行了一项实验，以研究大肠中发酵性不同的日粮对猪感染猪痢疾的病原体猪痢疾短螺旋体和猪鞭虫的影响。配制了两种含有有机种植成分的日粮。两种日粮均以小黑麦和大麦为基础，并分别添加了菜籽饼（日粮1）或干菊苣根和甜羽扇豆（日粮2）。该研究采用三因素设计，八组猪分别接受日粮1或日粮2，感染/未感染猪痢疾短螺旋体，感染/未感染猪鞭虫。喂食日粮2并感染猪痢疾短螺旋体的猪未患猪痢疾，且在研究期间任何猪中均未检测到猪痢疾短螺旋体。相比之下，喂食日粮1并感染猪痢疾短螺旋体的猪中，94%出现了猪痢疾的临床症状，并且在实验期间的某些时间点，所有猪的粪便中都排出了猪痢疾短螺旋体。与喂食日粮1的猪相比，喂食日粮2的猪体内猪鞭虫的数量较少，但差异不显著。喂食日粮1并同时感染两种病原体的猪出现猪痢疾临床症状的时间比仅感染猪痢疾短螺旋体 的猪更长。该研究表明，添加干菊苣根和甜羽扇豆中高发酵性碳水化合物的日粮可以保护猪不患猪痢疾，但对猪鞭虫没有任何显著影响。
