Turner Philip J
Infection Discovery Department, AstraZeneca, SK10 4TG Macclesfield, Cheshire, UK.
Diagn Microbiol Infect Dis. 2006 Nov;56(3):341-4. doi: 10.1016/j.diagmicrobio.2006.07.015. Epub 2006 Oct 17.
This article examines the activity of meropenem and imipenem against Pseudomonas aeruginosa isolates from the Meropenem Yearly Susceptibility Test Information Collection program between 1997 and 2005. In particular, it examines the activity of meropenem against imipenem-resistant strains and vice versa. Meropenem proved to be active against up to a 3rd of imipenem-resistant strains.
本文研究了美罗培南和亚胺培南对1997年至2005年美罗培南年度药敏试验信息收集项目中分离出的铜绿假单胞菌的活性。特别是,研究了美罗培南对亚胺培南耐药菌株的活性,反之亦然。结果证明,美罗培南对高达三分之一的亚胺培南耐药菌株具有活性。