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注意力缺陷/多动障碍与工作记忆:一种任务切换范式。

Attention-Deficit/Hyperactivity Disorder and working memory: a task switching paradigm.

作者信息

Wu K K, Anderson V, Castiello U

机构信息

Department of Clinical Psychology, Caritas Medical Centre, Hospital Authority of Hong Kong.

出版信息

J Clin Exp Neuropsychol. 2006 Nov;28(8):1288-306. doi: 10.1080/13803390500477267.

Abstract

This study investigated working memory (WM) in children with Attention-Deficit/Hyperactivity Disorder (ADHD) using a task switching paradigm with Stroop color-word stimuli which required participants to switch from color-naming to word-reading. High and low WM load conditions were compared by manipulation of task reminders as a tempo cue. The sample comprised 83 children with ADHD and 29 normal children comparable in age (aged 7 to 13). Within the ADHD group, participants were divided according to the presence or absence of Learning Disability (LD). Results indicated that children with ADHD had slower response times and less accurate responses in general, however, the ADHD groups were not consistently slower in the high WM load condition. Instead, an impairment in adjusting response speed to cope with higher task demands (i.e., high WM load condition) was found. These results do not support the previously documented association between ADHD and a primary deficit in WM for task switching. However, children with ADHD do demonstrate a specific difficulty in slowing down for a demanding task. Present findings suggest that earlier proposals of under-arousal and poor state regulation in ADHD deserve renewed attention.

摘要

本研究使用一种任务切换范式,采用斯特鲁普颜色-文字刺激,要求参与者从颜色命名切换到文字阅读,以此来调查患有注意力缺陷多动障碍(ADHD)的儿童的工作记忆(WM)。通过操纵任务提示作为节奏线索,比较了高工作记忆负荷条件和低工作记忆负荷条件。样本包括83名患有ADHD的儿童和29名年龄相当(7至13岁)的正常儿童。在ADHD组中,参与者根据是否存在学习障碍(LD)进行划分。结果表明,患有ADHD的儿童总体上反应时间较慢且反应准确性较低,然而,ADHD组在高工作记忆负荷条件下并非始终较慢。相反,发现他们在调整反应速度以应对更高任务要求(即高工作记忆负荷条件)方面存在障碍。这些结果不支持先前记录的ADHD与任务切换中工作记忆的主要缺陷之间的关联。然而,患有ADHD的儿童在面对要求较高的任务时确实表现出特定的减速困难。目前的研究结果表明,ADHD中先前提出的唤醒不足和状态调节不良值得重新关注。

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